"Since glaucoma has much in common with other important neurodegenerative disorders, our research may say something generally about connections of other nerves within the brain and what controls their maintenance." Association for Research in Vision and Ophthalmology (ARVO). Scientists find that jigsaw effect in glaucoma patients proves it is." Science Daily. Association for Research in Vision and Ophthalmology (ARVO). Scientists find that jigsaw effect in glaucoma patients proves it is." Science Daily. Using anti-inflammatory medications after glaucoma laser surgery is not helpful or necessary, new research concludes.Glaucoma is the most common cause of irreversible blindness in the world, and is ...
However, the team of investigators discovered during their analysis that as previously disabled optic nerve axons -- that can lead to vision loss -- recover, the remaining areas of permanent visual loss in one eye coincide with the areas that can still see in the other eye.Guests are welcome to use the fully equipped kitchen, which comes complete with a stove, fridge and microwave.Cafes and bars can also be found within a 5-minute walk of the property.Sponsel that helped unmask the more permanent interlocking jigsaw patterns once the eyes of his severely affected patients had been surgically stabilized," said Calkins.Sponsel has already seen how these findings have positively affected surgically stabilized patients who were previously worried about going blind."This quiet intentional sacrifice of some wires to save the rest, when there are decreasing resources to support them all (called apoptosis), is analogous to pruning some of the limbs on a stressed fruit tree so the other branches can continue to bear healthy fruit." According to the researchers, the cellular process used for pruning small optic nerve axons in glaucoma is "remarkably similar to the apoptotic mechanism that operates in the brains of people afflicted with Alzheimer's disease." "The extent and statistical strength of the jigsaw effect in conserving the binocular visual field among the clinical population turned out to be remarkably strong," said Sponsel.
"The entire phenomenon appears to be under the meticulous control of the brain." The paper is the first evidence in humans that the brain plays a part in pruning optic nerve axon cells.
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The brain, not the eye, controls the cellular process that leads to glaucoma, a new study finds.
The results may help develop treatments for one of the world’s leading causes of irreversible blindness, as well as contribute to the development of future therapies for preserving brain function in other age-related disorders such as Alzheimer’s. According to the researchers, the cellular process used for pruning small optic nerve axons in glaucoma is "remarkably similar to the apoptotic mechanism that operates in the brains of people afflicted with Alzheimer's disease."Eye check (stock image).
paper, "Refined Data Analysis Provides Clinical Evidence for Central Nervous System Control of Chronic Glaucomatous Neurodegeneration," vision scientists and ophthalmologists describe how they performed a data and symmetry analysis of 47 patients with moderate to severe glaucoma in both eyes.